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CS-W001157 4
Total: USD 88.00

(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid

  • CAS No. 2483-46-7

  • Cat. No. CS-W007599
  • Molecule weight346.42
  • Purity≥95%
  • MDL No.MFCD00038515

*For research and further manufacturing use only, not for direct human use.

(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid|CS-W007599

Structure of 2483-46-7

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General Information

  • CAS No. 2483-46-7
  • Cat. No. CS-W007599
  • Purity ≥95%
  • MDL No. MFCD00038515
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₃₀N₂O₆
  • Molecular Weight 346.42
  • Synonym(s) Boc-Lys(Boc)-OH
  • SMILES O=C(O)[C@H](CCCCNC(OC(C)(C)C)=O)NC(OC(C)(C)C)=O

Description

(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid serves as a key chiral building block for peptide synthesis, featuring two protected amine groups flanking a central aliphatic chain. The tert-butyl carbamate (Boc) moieties provide robust protection under acidic conditions while maintaining stability during coupling reactions. This bifunctional structure enables precise incorporation into complex peptide architectures, particularly in the design of cyclic or branched sequences where orthogonal protection is required.

Application

(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid serves as a valuable chiral building block for the synthesis of peptide-based scaffolds and cyclic heterocycles. The molecule enables efficient construction of dipeptide mimetics and side-chain functionalized analogs through orthogonal deprotection strategies. Its tert-butyl carbamate groups provide excellent stability under standard reaction conditions and facilitate selective activation, purification, and downstream derivatization in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   113.96
  • LogP   2.6593
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   7

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