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CS-W001157 4
Total: USD 88.00

Gefitinib impurity 2

  • CAS No. 246512-44-7

  • Cat. No. CS-0019903
  • Purity≥98%
  • MDL No.MFCD26395622

*For research and further manufacturing use only, not for direct human use.

Gefitinib impurity 2|CS-0019903

Structure of 246512-44-7

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General Information

  • CAS No. 246512-44-7
  • Cat. No. CS-0019903
  • Purity ≥98%
  • MDL No. MFCD26395622
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₃N₃O₄
  • Molecular Weight 309.37
  • Synonym(s) None
  • SMILES O=C(N)C1=CC(OCCCN2CCOCC2)=C(OC)C=C1N

Synthesis

  • Route1

    References

    • Wang, Ji-Quan; Gao, Mingzhang; Miller, Kathy D.; Sledge, George W.; Zheng, Qi-Huang Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 15 p. 4102 - 4106
  • Route2
    • 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzamide  Gefitinib Impurity|CS-0164136
      861453-16-9
    • ~%
    • Gefitinib impurity 2|CS-0019903
      246512-44-7

    References

    • NATCO PHARMA LIMITED; JYOTHI PRASAD, Ramanadham; PULLA REDDY, Muddasani; NAGESHWARA RAO, Bollepalli; VENKAIAH CHOWDARY, Nannapaneni Patent: WO2005/70909 A1, 2005 ; Location in patent: Page/Page column 29 ;
  • Route3
    • 4-(3-Chloropropyl)morpholine Pramoxine Impurity|CS-0229750
      7357-67-7
    • ~%
    • Gefitinib impurity 2|CS-0019903
      246512-44-7

    References

    • Wang, Ji-Quan; Gao, Mingzhang; Miller, Kathy D.; Sledge, George W.; Zheng, Qi-Huang Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 15 p. 4102 - 4106

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   100.04
  • LogP   0.4774
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   7

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