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CS-W001157 4
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3-Methyl-2H-chromen-2-one

  • CAS No. 2445-82-1

  • Cat. No. CS-0613418
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Methyl-2H-chromen-2-one|CS-0613418

Structure of 2445-82-1

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General Information

  • CAS No. 2445-82-1
  • Cat. No. CS-0613418
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈O₂
  • Molecular Weight 160.17
  • Synonym(s) None
  • SMILES O=C1C(C)=CC2=CC=CC=C2O1

Description

3-Methyl-2H-chromen-2-one is a bench-stable, electron-deficient chromenone scaffold featuring a methyl group at the 3-position. This substitution enhances regioselectivity in electrophilic functionalization and stabilizes the enone system under standard conditions. The compound serves as a key building block for bioactive heterocycles and natural product analogs.

Application

3-Methyl-2H-chromen-2-one serves as a versatile scaffold in synthetic organic chemistry, enabling efficient construction of bioactive heterocycles. Its inherent stability and compatibility with diverse functional groups facilitate downstream transformations, including nucleophilic additions and transition-metal-catalyzed couplings. The compound functions as a key building block in the synthesis of natural product analogs and pharmaceutical intermediates, offering predictable reactivity and straightforward purification.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H402
Precautionary Statements : P264-P270-P273-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   30.21
  • LogP   2.10142
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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