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CS-W001157 4
Total: USD 88.00

6-Bromocoumarin

  • CAS No. 19063-55-9

  • Cat. No. CS-W005186
  • Purity≥95%
  • MDL No.MFCD01327473

*For research and further manufacturing use only, not for direct human use.

6-Bromocoumarin|CS-W005186

Structure of 19063-55-9

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General Information

  • CAS No. 19063-55-9
  • Cat. No. CS-W005186
  • Purity ≥95%
  • MDL No. MFCD01327473
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₅BrO₂
  • Molecular Weight 225.04
  • Synonym(s) 6-Bromochromen-2-one
  • SMILES BrC1=CC=C(O2)C(C=CC2=O)=C1

Description

6-Bromocoumarin serves as a key building block in synthetic organic chemistry, featuring a bromine substituent at the 6-position that enables facile functionalization via palladium-catalyzed cross-coupling. This electron-deficient scaffold integrates readily into fluorescent probes and bioactive molecules, offering enhanced stability and predictable reactivity under standard conditions.

Application

6-Bromocoumarin serves as a versatile building block in synthetic organic chemistry, enabling efficient functionalization at the 6-position of the coumarin scaffold. Its bromine substituent facilitates palladium-catalyzed cross-coupling reactions, including Suzuki and Stille couplings, for the construction of biaryl and heteroaryl architectures. The compound exhibits excellent bench stability, ease of purification, and compatibility with a range of functional groups, making it well-suited for medicinal chemistry campaigns and the development of fluorescent probes or kinase inhibitors.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   30.21
  • LogP   2.5555
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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