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CS-W001157 4
Total: USD 88.00

γ-Carboline

  • CAS No. 244-69-9

  • Cat. No. CS-W006474
  • Purity≥97%
  • MDL No.MFCD00965976

*For research and further manufacturing use only, not for direct human use.

γ-Carboline|CS-W006474

Structure of 244-69-9

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General Information

  • CAS No. 244-69-9
  • Cat. No. CS-W006474
  • Purity ≥97%
  • MDL No. MFCD00965976
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₈N₂
  • Molecular Weight 168.19
  • Synonym(s) 5H-Pyrido[4,3-b]indole
  • SMILES C12=CC=NC=C1C3=C(C=CC=C3)N2

Description

5H-Pyrido[4,3-b]indole delivers a rigid, electron-rich heterocyclic scaffold ideal for constructing bioactive molecules. This fused tricyclic system combines enhanced stability with favorable π-conjugation, enabling efficient integration into pharmaceutical candidates and functional materials.

Application

5H-Pyrido[4,3-b]indole serves as a versatile heterocyclic scaffold in medicinal chemistry, enabling the construction of bioactive molecules through established functionalization at the pyridine and indole rings. Its structural rigidity and electron-rich character facilitate efficient coupling reactions and metal-catalyzed transformations, supporting rapid diversification for drug discovery applications.

Synthesis

  • Route1
    • null|null
      86775-99-7
    • ~73%
    • In-stock
      γ-Carboline|CS-W006474
      244-69-9

    References

    • Sako, Kumiko; Aoyama, Hiroshi; Sato, Shinichi; Hashimoto, Yuichi; Baba, Masanori Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3780 - 3790
  • Route2
    • 1-(Pyridin-4-yl)-1H-benzo[d][1,2,3]triazole|CS-0569193
      66571-30-0
    • ~67%
    • In-stock
      γ-Carboline|CS-W006474
      244-69-9

    References

    • Yutilov; Smolyar; Volchkov Pharmaceutical Chemistry Journal, 2000 , vol. 34, # 12 p. 661 - 662
  • Route3
    • null|null
      86776-00-3
    • ~98%
    • In-stock
      γ-Carboline|CS-W006474
      244-69-9

    References

    • Van Baelen, Gitte; Hostyn, Steven; Dhooghe, Liene; Tapolcsanyi, Pal; Matyus, Peter; Lemiere, Guy; Dommisse, Roger; Kaiser, Marcel; Brun, Reto; Cos, Paul; Maes, Louis; Hajos, Gyoergy; Riedl, Zsuzsanna; Nagy, Ildiko; Maes, Bert U.W.; Pieters, Luc Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 20 p. 7209 - 7217

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.7161
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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