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Structure of 243666-13-9
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2-(2,3,4-Trifluorophenyl)acetonitrile features a trifluorinated phenyl ring coupled to a nitrile-bearing acetyl side chain, delivering enhanced electron-withdrawing character and improved metabolic stability. This combination enables efficient integration into pharmaceutical scaffolds and synthetic intermediates requiring high functional group tolerance and structural rigidity under standard conditions.
2-(2,3,4-Trifluorophenyl)acetonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles and functionalized aryl derivatives. Its trifluorophenyl moiety enhances metabolic stability and modulates lipophilicity, while the nitrile group offers reliable reactivity in nucleophilic additions, reductions, and cyclizations. The compound exhibits excellent bench stability and compatibility with standard synthetic protocols, facilitating straightforward purification and integration into multi-step sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: