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CS-W001157 4
Total: USD 88.00

Lenalidomide-acetylene-C5-COOH

  • CAS No. 2429878-72-6

  • Cat. No. CS-0106899
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Lenalidomide-acetylene-C5-COOH|CS-0106899

Structure of 2429878-72-6

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General Information

  • CAS No. 2429878-72-6
  • Cat. No. CS-0106899
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₂N₂O₅
  • Molecular Weight 382.41
  • Synonym(s) Cereblon ligand-linker Conjugate
  • SMILES O=C1N(C2C(NC(CC2)=O)=O)CC3=C1C=CC=C3C#CCCCCCC(O)=O

Application

Lenalidomide-acetylene-C5-COOH serves as a versatile synthetic intermediate for constructing targeted covalent probes and macrocyclic architectures. The acetylene handle enables reliable CuAAC click chemistry, while the C5-carboxylic acid facilitates amide coupling or derivatization under standard conditions. This bifunctional scaffold offers excellent bench stability and compatibility with diverse reaction workflows, enabling efficient conjugation strategies in medicinal chemistry and chemical biology applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   103.78
  • LogP   1.8342
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   6

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