Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-(Methoxycarbonyl)nicotinic acid

  • CAS No. 24202-74-2

  • Cat. No. CS-0180901
  • Purity≥98%
  • MDL No.MFCD00111513

*For research and further manufacturing use only, not for direct human use.

4-(Methoxycarbonyl)nicotinic acid|CS-0180901

Structure of 24202-74-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 24202-74-2
  • Cat. No. CS-0180901
  • Purity ≥98%
  • MDL No. MFCD00111513
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO₄
  • Molecular Weight 181.15
  • Synonym(s) Cinchomeronic acid 4-methyl ester
  • SMILES O=C(O)C1=CN=CC=C1C(OC)=O

Description

4-(Methoxycarbonyl)nicotinic acid features a pyridine ring bearing both carboxylic acid and methoxycarbonyl groups at para positions, enabling direct conjugation in heterocyclic synthesis. This electron-deficient scaffold integrates readily into bioactive molecules, offering enhanced solubility and stability under standard conditions.

Application

4-(Methoxycarbonyl)nicotinic acid serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling efficient access to pyridine-based pharmacophores. Its dual functionality—carboxylic acid and ester groups—facilitates selective derivatization, including amidation, hydrolysis, and coupling reactions. The molecule exhibits excellent bench stability and is compatible with standard peptide coupling protocols, making it ideal for constructing heterocyclic scaffolds and API intermediates.

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      Furo[3,4-c]pyridine-1,3-dione|CS-W007774
      4664-08-8
    • ~45%
    • In-stock
      4-(Methoxycarbonyl)nicotinic acid|CS-0180901
      24202-74-2

    References

    • Procopiou, Panayiotis A.; Browning, Christopher; Gore, Paul M.; Lynn, Sean M.; Richards, Stephen A.; Slack, Robert J.; Sollis, Steven L. Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 20 p. 6097 - 6108
  • Route2
    • In-stock
      Furo[3,4-c]pyridine-1,3-dione|CS-W007774
      4664-08-8
    • null|null
      124-41-4
    • ~73%
    • In-stock
      4-(Methoxycarbonyl)nicotinic acid|CS-0180901
      24202-74-2

    References

    • Ketcha, Daniel M.; Gribble, Gordon W. Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5451 - 5457
  • Route3
    • null|null
      67-56-1
    • In-stock
      Furo[3,4-c]pyridine-1,3-dione|CS-W007774
      4664-08-8
    • null|null
      124-41-4
    • ~44%
    • In-stock
      4-(Methoxycarbonyl)nicotinic acid|CS-0180901
      24202-74-2

    References

    • GLAXO GROUP LIMITED Patent: WO2007/122156 A1, 2007 ; Location in patent: Page/Page column 90-91 ; WO 2007/122156 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   76.49
  • LogP   0.5664
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-(Methoxycarbonyl)nicotinic acid sigma4-(Methoxycarbonyl)nicotinic acid manufacturer4-(Methoxycarbonyl)nicotinic acid price4-(Methoxycarbonyl)nicotinic acid structure4-(Methoxycarbonyl)nicotinic acid SDSbuy 4-(Methoxycarbonyl)nicotinic acid4-(Methoxycarbonyl)nicotinic acid supplier4-(Methoxycarbonyl)nicotinic acid uses4-(Methoxycarbonyl)nicotinic acid molecular weightprice of 4-(Methoxycarbonyl)nicotinic acid4-(Methoxycarbonyl)nicotinic acid chemical name formula of 4-(Methoxycarbonyl)nicotinic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label