Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidine

  • CAS No. 2417014-06-1

  • Cat. No. CS-0368678
  • Molecule weight274.05
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidine|CS-0368678

Structure of 2417014-06-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 2417014-06-1
  • Cat. No. CS-0368678
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄BF₃N₂O₂
  • Molecular Weight 274.05
  • Synonym(s) None
  • SMILES FC(C1=NC=NC=C1B2OC(C)(C)C(C)(C)O2)(F)F

Description

This boronate-functionalized pyrimidine integrates readily into Suzuki-Miyaura coupling reactions under standard conditions, delivering trifluoromethyl-substituted heterocycles with high efficiency. The tetramethylborolane group ensures excellent stability and compatibility in diverse synthetic workflows.

Application

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables stable, air-tolerant handling and facilitates efficient coupling with aryl, heteroaryl, and vinyl halides under mild conditions. The trifluoromethylpyrimidine core provides a valuable pharmacophore in medicinal chemistry, offering enhanced metabolic stability and lipophilicity. This reagent functions reliably in diverse synthetic workflows, enabling rapid access to complex heterocyclic scaffolds with predictable regiochemistry and high functional group tolerance.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   44.24
  • LogP   1.7946
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2417014-06-1 sigma2417014-06-1 manufacturer2417014-06-1 price2417014-06-1 structure2417014-06-1 SDSbuy 2417014-06-12417014-06-1 supplier2417014-06-1 uses2417014-06-1 molecular weightprice of 2417014-06-12417014-06-1 chemical name formula of 2417014-06-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label