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CS-W001157 4
Total: USD 88.00

D-Mannitol

  • CAS No. 69-65-8

  • Cat. No. CS-2494
  • Purity≥97%
  • MDL No.MFCD00064287

*For research and further manufacturing use only, not for direct human use.

D-Mannitol|CS-2494

Structure of 69-65-8

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General Information

  • CAS No. 69-65-8
  • Cat. No. CS-2494
  • Purity ≥97%
  • MDL No. MFCD00064287
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄O₆
  • Molecular Weight 182.17
  • Synonym(s) Mannitol; Mannite
  • SMILES OC[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O

Description

Tetrahydroxydiboron (BBA) is an efficient borylating agent that can be used to borylate a wide variety of aryl and heteroaryl substrates with low Pd- and Ni-catalyst loads.Other reactions employing BBA as a reagent:Palladium-catalyzed boronation of vinyl cyclopropane, vinyl aziridine, and allyl acetate substrates.To facilitate catalytic transfer hydrogenations of simple alkenes and alkynes.Selective reducing agent for in situ N-oxide reduction of pyridine-N-oxides.As a substitute to bis(pinacolato) diboron for Miyaura borylation.

Synthesis

  • Route1

    References

    • Bulletin de la Societe Chimique de France, , vol. 2, # 7-8 p. 288 - 292
  • Route2

    References

    • Hricoviniova, Zuzana Tetrahedron Asymmetry, 2011 , vol. 22, # 11 p. 1184 - 1188
  • Route3

    References

    • ChemSusChem, , vol. 6, # 8 p. 1545 - 1555

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   121.38
  • LogP   -3.5854
  • H_Acceptors   6
  • H_Donors   6
  • Rotatable_Bonds   5

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