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CS-W001157 4
Total: USD 88.00

3-Methyl-1,2,4-triazine

  • CAS No. 24108-33-6

  • Cat. No. CS-0152715
  • Molecule weight95.10
  • Purity≥98%
  • MDL No.MFCD10000820

*For research and further manufacturing use only, not for direct human use.

3-Methyl-1,2,4-triazine|CS-0152715

Structure of 24108-33-6

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General Information

  • CAS No. 24108-33-6
  • Cat. No. CS-0152715
  • Purity ≥98%
  • MDL No. MFCD10000820
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅N₃
  • Molecular Weight 95.10
  • Synonym(s) 1,2,4-Triazine,3-methyl
  • SMILES CC1=NN=CC=N1

Description

3-Methyl-1,2,4-triazine is a nitrogen-rich heterocycle featuring a methyl group at the 3-position, enhancing its electron density and reactivity. This bench-stable compound serves as a key scaffold in medicinal chemistry and agrochemical synthesis, offering favorable solubility and compatibility with diverse reaction conditions.

Application

3-Methyl-1,2,4-triazine serves as a versatile heterocyclic building block in medicinal chemistry and agrochemical synthesis. Its electron-deficient triazine core facilitates nucleophilic substitution at C5 and enables regioselective functionalization under mild conditions. The methyl group enhances solubility and metabolic stability, while the scaffold exhibits excellent compatibility with common coupling reactions and protecting group strategies. This compound functions as a key intermediate in the construction of bioactive molecules and is valued for its bench stability and straightforward purification.

Synthesis

  • Route1
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      131543-46-9
    • Acetimidohydrazide hydrochloride|CS-W005939
      39254-63-2
    • ~%
    • In-stock
      3-Methyl-1,2,4-triazine|CS-0152715
      24108-33-6

    References

    • Courcot, Blandine; Tran, Diem Ngan; Fraisse, Bernard; Bonhomme, Francois; Marsura, Alain; Ghermani, Nour Eddine Chemistry - A European Journal, 2007 , vol. 13, # 12 p. 3414 - 3423

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.67
  • LogP   0.18002
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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