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Structure of 2410440-12-7
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Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentane-1-carboxylate is a sterically hindered boronate ester featuring a rigid bicyclo[1.1.1]pentane core. This configuration imparts exceptional stability and resistance to protodeboronation, enabling reliable coupling under mild conditions. The molecule integrates seamlessly into cross-coupling reactions, delivering high functional group tolerance and predictable reactivity in complex synthesis.
Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentane-1-carboxylate serves as a stable, bench-friendly boron building block for Suzuki-Miyaura coupling reactions. The bicyclo[1.1.1]pentane core imparts excellent metabolic stability and improved bioavailability, making it a valuable scaffold in medicinal chemistry. Its tetramethyl-substituted boronate group enables high functional group tolerance and reliable coupling efficiency under standard reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: