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Structure of 2409005-96-3
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This piperidine-2,6-dione derivative features a 5-bromo-6-fluoro-1-oxoisoindolin-2-yl substituent, delivering enhanced electronic modulation and metabolic stability. The fused isoindolinone core enables efficient integration into complex scaffolds, while the bromo and fluoro groups facilitate downstream functionalization via cross-coupling. This compound serves as a high-value building block in medicinal chemistry, particularly for kinase inhibitor and CNS-targeted lead development.
3-(5-Bromo-6-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione serves as a versatile building block for the synthesis of isoindolinone-based scaffolds. Its bromo and fluoro substituents enable late-stage functionalization via palladium-catalyzed cross-coupling reactions. The diketone functionality provides a robust platform for further derivatization, including reductive amination and condensation chemistry, while maintaining bench stability and ease of purification in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: