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CS-W001157 4
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3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonyl fluoride

  • CAS No. 2393030-89-0

  • Cat. No. CS-0101419
  • Molecule weight286.13
  • Purity≥95%
  • MDL No.MFCD30487497

*For research and further manufacturing use only, not for direct human use.

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonyl fluoride|CS-0101419

Structure of 2393030-89-0

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General Information

  • CAS No. 2393030-89-0
  • Cat. No. CS-0101419
  • Purity ≥95%
  • MDL No. MFCD30487497
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆BFO₄S
  • Molecular Weight 286.13
  • Synonym(s) None
  • SMILES O=S(C1=CC=CC(B2OC(C)(C)C(C)(C)O2)=C1)(F)=O

Description

This boronate-containing sulfonamide integrates a tetramethyl-dioxaborolane group for efficient cross-coupling, delivering enhanced stability and compatibility with diverse reaction conditions. The para-fluorosulfonyl moiety enables selective functionalization in synthetic workflows.

Application

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonyl fluoride serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. The sulfonyl fluoride group enables orthogonal reactivity and facilitates downstream derivatization, while the tetramethylborolane moiety ensures high functional group tolerance and compatibility with diverse reaction conditions. Its stability simplifies handling and purification, making it well-suited for modular synthesis of biaryl sulfones in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   1.644
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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