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Structure of 2377644-59-0
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This benzoic acid derivative features a 2,4-dioxotetrahydropyrimidine moiety that imparts enhanced reactivity in heterocyclic synthesis. The conjugated system enables efficient integration into bioactive scaffolds, while the carboxylic acid group facilitates derivatization under mild conditions. Bench-stable and moisture-tolerant, it serves as a strategic building block for medicinal chemistry campaigns targeting kinase inhibitors and antiviral agents.
3-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)benzoic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyrimidine-fused scaffolds via standard condensation and cyclization protocols. The ortho-substituted benzoic acid moiety provides enhanced solubility and facilitates downstream derivatization, while the 2,4-dioxotetrahydropyrimidine core exhibits predictable reactivity in amide coupling and nucleophilic addition reactions. Its bench-stable nature and compatibility with common functional groups support reliable application in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: