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CS-W001157 4
Total: USD 88.00

3-Fluoro-4-thiomorpholin-4-ylaniline

  • CAS No. 237432-11-0

  • Cat. No. CS-0037969
  • Purity≥97%
  • MDL No.MFCD09953533

*For research and further manufacturing use only, not for direct human use.

3-Fluoro-4-thiomorpholin-4-ylaniline|CS-0037969

Structure of 237432-11-0

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General Information

  • CAS No. 237432-11-0
  • Cat. No. CS-0037969
  • Purity ≥97%
  • MDL No. MFCD09953533
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃FN₂S
  • Molecular Weight 212.29
  • Synonym(s) 3-Fluoro-4-thiomorpholinoaniline
  • SMILES C1=CC(=C(C=C1N)F)N2CCSCC2

Description

3-Fluoro-4-thiomorpholin-4-ylaniline features a fluorinated aromatic core paired with a thiomorpholinyl amine handle, delivering enhanced solubility and metabolic stability. This electron-rich scaffold integrates readily into pharmaceutical intermediates, enabling efficient coupling in late-stage functionalization. The pendant thiomorpholine moiety enhances target engagement through favorable polar interactions.

Application

3-Fluoro-4-thiomorpholin-4-ylaniline serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds. Its fluorinated aromatic core provides enhanced metabolic stability and modulated electronic properties, while the thiomorpholinyl amine functionality offers favorable solubility and hydrogen-bonding capacity. The molecule demonstrates robust bench stability and compatibility with standard coupling reactions, facilitating efficient synthesis of kinase inhibitors and other pharmaceutical candidates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.26
  • LogP   1.9611
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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