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CS-W001157 4
Total: USD 88.00

2-(Methoxymethyl)pyridine

  • CAS No. 23579-92-2

  • Cat. No. CS-0150187
  • Purity≥96%
  • MDL No.MFCD00030825

*For research and further manufacturing use only, not for direct human use.

2-(Methoxymethyl)pyridine|CS-0150187

Structure of 23579-92-2

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General Information

  • CAS No. 23579-92-2
  • Cat. No. CS-0150187
  • Purity ≥96%
  • MDL No. MFCD00030825
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NO
  • Molecular Weight 123.15
  • Synonym(s) Pyridine, 2-(methoxymethyl)-
  • SMILES COCC1=CC=CC=N1

Description

2-(Methoxymethyl)pyridine features a pyridine ring bearing a methoxymethyl substituent at the 2-position, delivering enhanced solubility and reactivity in cross-coupling and functionalization processes. This bench-stable heterocycle integrates readily into pharmaceutical intermediates and ligand design due to its electron-rich character and compatibility under standard conditions.

Application

2-(Methoxymethyl)pyridine serves as a versatile pyridine-based building block for medicinal chemistry and catalyst development. Its methoxymethyl side chain enables selective functionalization at the 2-position, offering improved solubility and metabolic stability in bioactive molecules. The group is compatible with standard coupling reactions and can be selectively cleaved or modified under mild conditions, facilitating downstream derivatization. Bench-stable and readily purified, it functions effectively in multistep syntheses and API intermediate construction.

Synthesis

  • Route1

    References

    • US3966945 A1, ;
  • Route2
    • null|null
      4377-33-7
    • ~%
    • In-stock
      2-(Methoxymethyl)pyridine|CS-0150187
      23579-92-2

    References

    • US3966945 A1, ;
  • Route3
    • In-stock
      2-Pyridinemethanol|CS-W020042
      586-98-1
    • null|null
      74-88-4
    • ~%
    • In-stock
      2-(Methoxymethyl)pyridine|CS-0150187
      23579-92-2

    References

    • US3966945 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   22.12
  • LogP   1.228
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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