(R)-3-(tert-Butyl)-4-(2,6-dimethoxy-3,5-dimethylphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole

Name: (R)-3-(tert-Butyl)-4-(2,6-dimethoxy-3,5-dimethylphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 2351219-88-8
Cat. No. CS-0092205
Purity≥97%
MDL No.MFCD32641159

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(R)-3-(tert-Butyl)-4-(2,6-dimethoxy-3,5-dimethylphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole|CS-0092205

Structure of 2351219-88-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 2351219-88-8
Cat. No. CS-0092205
Purity ≥97%
MDL No. MFCD32641159
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₁H₂₇O₃P
Molecular Weight 358.41
Synonym(s) (3R)-4-(2,6-Dimethoxy-3,5-dimethylphenyl)-3-(2-methyl-2-propanyl)-2,3-dihydro-1,3-benzoxaphosphole
SMILES COC1=C(C)C=C(C)C(OC)=C1C2=C([P@@](C(C)(C)C)CO3)C3=CC=C2

Description

(R)-3-(tert-Butyl)-4-(2,6-dimethoxy-3,5-dimethylphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole is a chiral phosphole derivative featuring a sterically shielded tert-butyl group and an electron-rich aryl moiety. This bench-stable compound integrates readily into asymmetric catalysis workflows, where its rigid, three-dimensional architecture enables precise stereocontrol in transition metal-mediated transformations.

Application

(R)-3-(tert-Butyl)-4-(2,6-dimethoxy-3,5-dimethylphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole serves as a sterically encumbered, bench-stable phosphole derivative enabling selective P–C bond formation in transition-metal-catalyzed cross-coupling reactions. Its ortho-dimethylated aryl substituent enhances stability and modulates electronic properties, while the chiral oxaphosphole core facilitates stereocontrolled synthesis of phosphorus-containing heterocycles. Functions effectively as a building block in the construction of biologically relevant scaffolds and catalyst precursors.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 27.69
LogP 5.24324
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 3

Key Words

2351219-88-8 sigma2351219-88-8 manufacturer2351219-88-8 price2351219-88-8 structure2351219-88-8 SDSbuy 2351219-88-82351219-88-8 supplier2351219-88-8 uses2351219-88-8 molecular weightprice of 2351219-88-82351219-88-8 chemical name formula of 2351219-88-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(R)-3-(tert-Butyl)-4-(2,6-dimethoxy-3,5-dimethylphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole

CAS No. 2351219-88-8

Recommended Products