(R)-1,2,3,4-Tetrahydronaphthalen-1-amine

Name: (R)-1,2,3,4-Tetrahydronaphthalen-1-amine
Brand: ChemScene
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CAS No. 23357-46-2
Cat. No. CS-W007717
Purity≥95%
MDL No.MFCD00671629

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-1,2,3,4-Tetrahydronaphthalen-1-amine|CS-W007717

Structure of 23357-46-2

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General Information

CAS No. 23357-46-2
Cat. No. CS-W007717
Purity ≥95%
MDL No. MFCD00671629
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₃N
Molecular Weight None
Synonym(s) 1-naphthalenamine, 1,2,3,4-tetrahydro-, (1R)-
SMILES N[C@@H]1CCCC2=C1C=CC=C2

Description

(R)-1,2,3,4-Tetrahydronaphthalen-1-amine is a chiral amine scaffold featuring a rigid, electron-rich tetralin core. This bench-stable derivative enables direct incorporation into asymmetric synthesis workflows, offering enhanced stereocontrol in catalyst design and pharmaceutical intermediates.

Application

(R)-1,2,3,4-Tetrahydronaphthalen-1-amine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through established amine functionalization pathways. Its rigid, aromatic-heterocyclic framework provides structural stability and predictable stereochemical control, facilitating efficient derivatization for target compound libraries. The compound exhibits good bench stability and compatibility with standard coupling reactions, making it well-suited for use in multi-step synthetic sequences requiring high reproducibility and functional group tolerance.

Safety Information

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GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: 2735
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H314-H318-H412
Precautionary Statements : P260-P264-P270-P280-P301+P310-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P363-P405-P501

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Computational Chemistry Data

TPSA 26.02
LogP 2.0227
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-1,2,3,4-Tetrahydronaphthalen-1-amine

CAS No. 23357-46-2

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