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CS-W001157 4
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(Naphthalen-1-ylmethyl)triphenylphosphonium chloride

  • CAS No. 23277-00-1

  • Cat. No. CS-0186107
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(Naphthalen-1-ylmethyl)triphenylphosphonium chloride|CS-0186107

Structure of 23277-00-1

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General Information

  • CAS No. 23277-00-1
  • Cat. No. CS-0186107
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₉H₂₄ClP
  • Molecular Weight 438.93
  • Synonym(s) Triphenyl(1-naphthylmethyl)phosphonium Chloride
  • SMILES C1=CC=C(C=C1)[P+](CC2=CC=CC3=CC=CC=C32)(C4=CC=CC=C4)C5=CC=CC=C5.[Cl-]

Description

Naphthalen-1-ylmethyltriphenylphosphonium chloride serves as a stable, bench-ready phosphonium salt for organophosphorus synthesis. The naphthalene moiety enhances π-stacking and solubility in organic media, while the triphenylphosphonium core facilitates Wittig-type olefination and phase-transfer catalysis under mild conditions.

Application

(Naphthalen-1-ylmethyl)triphenylphosphonium chloride serves as a reliable Wittig reagent precursor, enabling efficient olefination of aldehydes and ketones under standard conditions. Its naphthylmethyl group enhances stability and facilitates purification via crystallization. The compound exhibits robust functional group tolerance and is well-suited for the synthesis of conjugated alkenes and styrenyl derivatives in medicinal chemistry and materials research.

Synthesis

  • Route1
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      603-35-0
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      86-52-2
    • ~92%
    • In-stock
      (Naphthalen-1-ylmethyl)triphenylphosphonium chloride|CS-0186107
      23277-00-1

    References

    • Beck; Jendralla; Kammermeier Tetrahedron, 1994 , vol. 50, # 16 p. 4691 - 4698

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.3379
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   5

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