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CS-W001157 4
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(4-Methylbenzyl)triphenylphosphonium chloride

  • CAS No. 1530-37-6

  • Cat. No. CS-0198951
  • Purity≥97%
  • MDL No.MFCD00031581

*For research and further manufacturing use only, not for direct human use.

(4-Methylbenzyl)triphenylphosphonium chloride|CS-0198951

Structure of 1530-37-6

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General Information

  • CAS No. 1530-37-6
  • Cat. No. CS-0198951
  • Purity ≥97%
  • MDL No. MFCD00031581
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₂₄ClP
  • Molecular Weight 402.90
  • Synonym(s) None
  • SMILES CC(C=C1)=CC=C1C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Cl-]

Description

This bench-stable phosphonium salt features a (4-methylbenzyl) group attached to a triphenylphosphonium cation, enabling efficient Wittig-type olefination reactions. The electron-donating methyl substituent enhances reactivity while maintaining stability under standard conditions.

Application

(4-Methylbenzyl)triphenylphosphonium chloride serves as a reliable precursor for Wittig reagents, enabling efficient olefination reactions under standard conditions. The benzylic phosphonium salt exhibits excellent bench stability and facilitates the synthesis of α,β-unsaturated carbonyl compounds with predictable stereochemistry. Its functional group tolerance and ease of handling make it well-suited for iterative synthetic sequences in complex molecule construction.

Synthesis

  • Route1
    • null|null
      104-82-5
    • null|null
      603-35-0
    • ~86%
    • In-stock
      (4-Methylbenzyl)triphenylphosphonium chloride|CS-0198951
      1530-37-6

    References

    • Cui, Mengchao; Li, Zijing; Tang, Ruikun; Jia, Hongmei; Liu, Boli European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 2908 - 2916
  • Route2
    • null|null
      104-82-5
    • ~65%
    • In-stock
      (4-Methylbenzyl)triphenylphosphonium chloride|CS-0198951
      1530-37-6

    References

    • Mallory, Frank B.; Mallory, Clelia W. Journal of Organic Chemistry, 1983 , vol. 48, # 4 p. 526 - 532
  • Route3

    References

    • Imrie, C.; Modro, T. A.; Rohwer, E. R.; Wagener, C. C. P. Journal of Organic Chemistry, 1993 , vol. 58, # 21 p. 5643 - 5649

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.49312
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   5

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