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CS-W001157 4
Total: USD 88.00

4,5,6,7-Tetrahydroindazole

  • CAS No. 2305-79-5

  • Cat. No. CS-0052539
  • Purity≥97%
  • MDL No.MFCD00014565

*For research and further manufacturing use only, not for direct human use.

4,5,6,7-Tetrahydroindazole|CS-0052539

Structure of 2305-79-5

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General Information

  • CAS No. 2305-79-5
  • Cat. No. CS-0052539
  • Purity ≥97%
  • MDL No. MFCD00014565
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀N₂
  • Molecular Weight 122.17
  • Synonym(s) None
  • SMILES N1=CC2=C(N1)CCCC2

Description

4,5,6,7-Tetrahydro-1H-indazole is a bench-stable, electron-rich heterocycle featuring a saturated indazole core. This structure integrates seamlessly into medicinal chemistry scaffolds, offering favorable solubility and compatibility in synthetic transformations. The saturated ring system enhances metabolic stability while maintaining hydrogen-bonding capacity for target engagement.

Application

4,5,6,7-Tetrahydro-1H-indazole serves as a versatile heterocyclic building block in medicinal chemistry, offering a stable, nitrogen-rich scaffold with defined regiochemistry. Its saturated core exhibits favorable solubility and bench stability, enabling efficient functionalization at the 1- and 3-positions. The compound functions as a key intermediate in the synthesis of kinase inhibitors and other bioactive molecules, participating reliably in coupling reactions and electrophilic substitutions under standard conditions.

Synthesis

  • Route1
    • null|null
      96227-96-2
    • ~%
    • In-stock
      4,5,6,7-Tetrahydroindazole|CS-0052539
      2305-79-5

    References

    • Journal of the American Chemical Society, , vol. 107, p. 3686
  • Route2
    • null|null
      96227-97-3
    • ~%
    • In-stock
      4,5,6,7-Tetrahydroindazole|CS-0052539
      2305-79-5

    References

    • Journal of the American Chemical Society, , vol. 107, p. 3686
  • Route3
    • null|null
      96227-98-4
    • ~%
    • In-stock
      4,5,6,7-Tetrahydroindazole|CS-0052539
      2305-79-5

    References

    • Journal of the American Chemical Society, , vol. 107, p. 3686

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   1.2885
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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