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CS-W001157 4
Total: USD 88.00

Pyrrolidine-2-thione

  • CAS No. 2295-35-4

  • Cat. No. CS-W013703
  • Molecule weight101.17
  • Purity≥97%
  • MDL No.MFCD00049351

*For research and further manufacturing use only, not for direct human use.

Pyrrolidine-2-thione|CS-W013703

Structure of 2295-35-4

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General Information

  • CAS No. 2295-35-4
  • Cat. No. CS-W013703
  • Purity ≥97%
  • MDL No. MFCD00049351
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇NS
  • Molecular Weight 101.17
  • Synonym(s) 2-Pyrrolethione, tetrahydro-, (Z)-
  • SMILES S=C1NCCC1

Description

Pyrrolidine-2-thione delivers a reactive thione functionality within a saturated heterocyclic framework, enabling direct incorporation into diverse synthetic scaffolds. This bench-stable compound features high nucleophilicity at sulfur and enhanced solubility in polar organic media, facilitating efficient coupling reactions under mild conditions.

Application

Pyrrolidine-2-thione serves as a versatile building block in synthetic organic chemistry, enabling efficient access to thioamide-containing heterocycles and sulfur-functionalized scaffolds. Its reactive thione group facilitates nucleophilic addition and metal-catalyzed transformations, while the pyrrolidine core provides structural rigidity and favorable solubility. The compound exhibits bench stability and compatibility with common functional groups, making it suitable for modular synthesis workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   0.6972
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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