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CS-W001157 4
Total: USD 88.00

2-Ethylbenzaldehyde

  • CAS No. 22927-13-5

  • Cat. No. CS-W007787
  • Purity≥97%
  • MDL No.MFCD02261766

*For research and further manufacturing use only, not for direct human use.

2-Ethylbenzaldehyde|CS-W007787

Structure of 22927-13-5

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General Information

  • CAS No. 22927-13-5
  • Cat. No. CS-W007787
  • Purity ≥97%
  • MDL No. MFCD02261766
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O
  • Molecular Weight 134.18
  • Synonym(s) o-Ethylbenzaldehyde
  • SMILES O=CC1=CC=CC=C1CC

Application

2-Ethylbenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted aromatic scaffolds via standard functional group transformations. Its aldehyde functionality facilitates nucleophilic additions, condensations, and coupling reactions with high chemoselectivity. The ortho-ethyl substituent provides steric and electronic modulation, enhancing stability and directing reactivity in subsequent derivatizations. Ideal for medicinal chemistry and process development, it offers reliable bench stability and straightforward purification, making it well-suited for scale-up applications.

Synthesis

  • Route1
    • In-stock
      1-Bromo-2-ethylbenzene|CS-W016966
      1973-22-4
    • null|null
      68-12-2
    • ~93%
    • In-stock
      2-Ethylbenzaldehyde|CS-W007787
      22927-13-5

    References

    • Hansen, Marvin Martin; He, John Xiaoqiang; Honigschmidt, Nicholas Allan; Koch, Daniel James; Kohn, Todd Jonathan; Rocco, Vincent Patrick; Spinazze, Patrick Gianpietro; Takeuchi, Kumiko Patent: US2004/6229 A1, 2004 ; Location in patent: Page/Page column 91 ; US 20040006229 A1
  • Route2

    References

    • Takahashi, Tohru; Yoshimura, Masatoshi; Suzuka, Hiroyasu; Maegawa, Tomohiro; Sawama, Yoshinari; Monguchi, Yasunari; Sajiki, Hironao Tetrahedron, 2012 , vol. 68, # 39 p. 8293 - 8299
  • Route3
    • null|null
      21450-63-5
    • null|null
      68-12-2
    • ~%
    • In-stock
      2-Ethylbenzaldehyde|CS-W007787
      22927-13-5

    References

    • US2008/255230 A1, ; Page/Page column 15; 18-19 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.0615
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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