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CS-W001157 4
Total: USD 88.00

2-Ethynylbenzaldehyde

  • CAS No. 38846-64-9

  • Cat. No. CS-W005336
  • Purity≥98%
  • MDL No.MFCD04039985

*For research and further manufacturing use only, not for direct human use.

2-Ethynylbenzaldehyde|CS-W005336

Structure of 38846-64-9

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General Information

  • CAS No. 38846-64-9
  • Cat. No. CS-W005336
  • Purity ≥98%
  • MDL No. MFCD04039985
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆O
  • Molecular Weight 130.14
  • Synonym(s) 2-Formylphenylacetylene
  • SMILES O=CC1=CC=CC=C1C#C

Application

2-Ethynylbenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted heterocycles and conjugated systems via [2+2] cycloadditions and Sonogashira coupling. Its aldehyde and terminal alkyne functionalities offer orthogonal reactivity, facilitating sequential functionalization. Bench-stable and amenable to purification by distillation or chromatography, it functions reliably in multi-step syntheses targeting pharmaceutical intermediates and advanced materials.

Synthesis

  • Route1

    References

    • Dell'Acqua, Monica; Facoetti, Diego; Abbiati, Giorgio; Rossi, Elisabetta Synthesis, 2010 , # 14 art. no. Z06110SS, p. 2367 - 2378
  • Route2
    • null|null
      396717-20-7
    • ~87%
    • In-stock
      2-Ethynylbenzaldehyde|CS-W005336
      38846-64-9

    References

    • Korich, Andrew L.; Hughes, Thomas S. Organic Letters, 2008 , vol. 10, # 23 p. 5405 - 5408
  • Route3
    • null|null
      88180-41-0
    • ~12%
    • null|null
      480-90-0
    • In-stock
      2-Ethynylbenzaldehyde|CS-W005336
      38846-64-9

    References

    • Trahanovsky,W.S.; Amah,A.N.; Cassady,T.J. Journal of the American Chemical Society, 1984 , vol. 106, p. 2696

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   1.4804
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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