Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(1-Ethyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)boronic acid

  • CAS No. 2287228-20-8

  • Cat. No. CS-0101382
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1-Ethyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)boronic acid|CS-0101382

Structure of 2287228-20-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 2287228-20-8
  • Cat. No. CS-0101382
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈BF₃N₂O₂
  • Molecular Weight 207.95
  • Synonym(s) [1-Ethyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]boronic acid
  • SMILES OB(O)C1=CN(N=C1C(F)(F)F)CC

Description

This boronate moiety integrates a trifluoromethyl group at the pyrazole C4 position, enhancing electron deficiency and metabolic stability. The ethyl substituent at N1 improves solubility and reduces aggregation. Designed for efficient Suzuki-Miyaura coupling under standard conditions, this bench-stable reagent enables rapid access to fluorinated heteroaryl architectures in medicinal chemistry and materials synthesis.

Application

(1-Ethyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)boronic acid serves as a stable, bench-ready building block for Suzuki-Miyaura cross-coupling reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the pyrazole core provides a rigid, polar scaffold suitable for medicinal chemistry applications. The boronic acid functionality enables efficient coupling with aryl and heteroaryl halides under mild conditions, offering high functional group tolerance and straightforward purification.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   58.28
  • LogP   -0.3984
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2287228-20-8 sigma2287228-20-8 manufacturer2287228-20-8 price2287228-20-8 structure2287228-20-8 SDSbuy 2287228-20-82287228-20-8 supplier2287228-20-8 uses2287228-20-8 molecular weightprice of 2287228-20-82287228-20-8 chemical name formula of 2287228-20-8
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label