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CS-W001157 4
Total: USD 88.00

2-(4-(Methoxycarbonyl)phenyl)acetic acid

  • CAS No. 22744-12-3

  • Cat. No. CS-W006135
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(4-(Methoxycarbonyl)phenyl)acetic acid|CS-W006135

Structure of 22744-12-3

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General Information

  • CAS No. 22744-12-3
  • Cat. No. CS-W006135
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀O₄
  • Molecular Weight 194.18
  • Synonym(s) 4-Carboxymethylbenzoic acid methyl ester
  • SMILES O=C(O)CC1=CC=C(C(OC)=O)C=C1

Description

2-(4-(Methoxycarbonyl)phenyl)acetic acid integrates a para-methoxycarbonyl aryl group with a carboxylic acid-bearing side chain, enabling direct conjugation in bioconjugation workflows. This bench-stable derivative facilitates efficient coupling to amines and supports modular synthesis of functionalized aromatic systems under standard conditions.

Application

2-(4-(Methoxycarbonyl)phenyl)acetic acid serves as a versatile building block for synthesizing substituted benzoic acids and biaryl systems. Its carboxylic acid functionality enables direct amidation, esterification, or coupling reactions, while the para-methoxycarbonyl group provides orthogonal reactivity for further functionalization. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.6
  • LogP   1.1003
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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