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CS-W001157 4
Total: USD 88.00

2,4,6-Triisopropylbenzenethiol

  • CAS No. 22693-41-0

  • Cat. No. CS-0654760
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,4,6-Triisopropylbenzenethiol|CS-0654760

Structure of 22693-41-0

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General Information

  • CAS No. 22693-41-0
  • Cat. No. CS-0654760
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₄S
  • Molecular Weight 236.42
  • Synonym(s) None
  • SMILES CC(C)C1=CC(=C(C(=C1)C(C)C)S)C(C)C

Description

2,4,6-Triisopropylbenzenethiol features a sterically shielded aromatic core that enhances stability and resistance to oxidation. The thiol group enables reliable coupling in cross-coupling reactions and surface functionalization. This bench-stable reagent integrates seamlessly into synthetic workflows requiring robust, moisture-tolerant sulfur handles.

Application

2,4,6-Triisopropylbenzenethiol serves as a sterically encumbered thiophenol derivative that facilitates selective thiol-based conjugations and acts as a robust ligand in transition metal catalysis. Its bulky triisopropyl substituents confer enhanced stability and minimize unwanted side reactions, enabling reliable use in functional group interconversions and heterocycle synthesis. The compound exhibits excellent bench stability and simplifies purification in complex reaction mixtures.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H302+H312+H332-H314
Precautionary Statements : P210-P260-P261-P264-P270-P271-P280-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P370+P378-P403-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   5.3455
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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