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CS-W001157 4
Total: USD 88.00

(4-(N-Methylsulfamoyl)phenyl)boronic acid

  • CAS No. 226396-31-2

  • Cat. No. CS-0036582
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4-(N-Methylsulfamoyl)phenyl)boronic acid|CS-0036582

Structure of 226396-31-2

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General Information

  • CAS No. 226396-31-2
  • Cat. No. CS-0036582
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀BNO₄S
  • Molecular Weight 215.04
  • Synonym(s) (4-METHYLAMINOSULPHONYL)BENZENE BORONIC ACID
  • SMILES CNS(=O)(=O)C1=CC=C(C=C1)B(O)O

Description

This boronic acid features a methylsulfamoyl group at the para position, enhancing solubility and metabolic stability. The boronate moiety enables efficient Suzuki-Miyaura coupling under standard conditions, delivering arylated products with high fidelity. Designed for robust performance in medicinal chemistry applications.

Application

(4-(N-Methylsulfamoyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds with enhanced solubility and metabolic stability. The N-methylsulfamoyl group imparts favorable functional group tolerance and bench stability, facilitating straightforward purification and integration into complex molecular architectures relevant to medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   86.63
  • LogP   -1.7255
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   3

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