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CS-W001157 4
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(4-Aminosulfonylphenyl)boronic acid

  • CAS No. 613660-87-0

  • Cat. No. CS-W005026
  • Purity≥98%
  • MDL No.MFCD06659839

*For research and further manufacturing use only, not for direct human use.

(4-Aminosulfonylphenyl)boronic acid|CS-W005026

Structure of 613660-87-0

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General Information

  • CAS No. 613660-87-0
  • Cat. No. CS-W005026
  • Purity ≥98%
  • MDL No. MFCD06659839
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈BNO₄S
  • Molecular Weight 201.01
  • Synonym(s) 4-(Aminosulphonyl)benzeneboronic acid
  • SMILES N[S](=O)(=O)C1=CC=C(C=C1)B(O)O

Description

This boronic acid features a para-aminosulfonyl group that enhances solubility and facilitates conjugation in bioconjugate chemistry. The boronate moiety enables efficient Suzuki-Miyaura coupling under standard conditions, while the electron-withdrawing sulfonamide imparts stability and directs regioselective functionalization.

Application

(4-Aminosulfonylphenyl)boronic acid serves as a versatile building block for Suzuki-Miyaura cross-coupling reactions, enabling the construction of biaryl scaffolds with high functional group tolerance. The pendant sulfonamide group enhances solubility and provides a handle for further derivatization, while the boronic acid moiety offers reliable stability under standard bench conditions and facilitates straightforward purification. Widely employed in medicinal chemistry and materials science, it functions effectively in the synthesis of bioactive heterocycles and conjugated systems.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   100.62
  • LogP   -1.9862
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   2

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