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CS-W001157 4
Total: USD 88.00

6-Methoxynaphthalen-1-ol

  • CAS No. 22604-07-5

  • Cat. No. CS-W006292
  • Purity≥96%
  • MDL No.MFCD03695468

*For research and further manufacturing use only, not for direct human use.

6-Methoxynaphthalen-1-ol|CS-W006292

Structure of 22604-07-5

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General Information

  • CAS No. 22604-07-5
  • Cat. No. CS-W006292
  • Purity ≥96%
  • MDL No. MFCD03695468
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₀O₂
  • Molecular Weight 174.20
  • Synonym(s) 6-METHOXY-1-NAPHTHOL
  • SMILES OC1=C2C=CC(OC)=CC2=CC=C1

Description

6-Methoxynaphthalen-1-ol features a naphthalene core with a hydroxyl group at position 1 and a methoxy substituent at position 6, delivering enhanced solubility and stability. This electron-rich scaffold enables direct incorporation into synthetic routes for pharmaceutical intermediates and functional materials, particularly in photoluminescent applications where its extended aromatic system facilitates efficient energy transfer.

Application

6-Methoxynaphthalen-1-ol serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted naphthalene scaffolds. Its phenolic hydroxyl group offers controlled reactivity for derivatization, while the methoxy substituent enhances solubility and modulates electronic properties. The compound exhibits good bench stability and facilitates coupling reactions under mild conditions, supporting its use in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Kumar, Subodh; Saravanan, Srinivasan; Reuben, Peter; Kumar, Atul Journal of Heterocyclic Chemistry, 2005 , vol. 42, # 7 p. 1345 - 1355
  • Route2

    References

    • Warner-Lambert Company Patent: US4767776 A1, 1988 ;
  • Route3
    • null|null
      99618-28-7
    • ~62%
    • In-stock
      6-Methoxynaphthalen-1-ol|CS-W006292
      22604-07-5

    References

    • Sibi, M.P.; Dankwardt, J.W.; Snieckus, V. Journal of Organic Chemistry, 1986 , vol. 51, # 2 p. 271 - 273

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   2.554
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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