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CS-W001157 4
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3-((4-(Piperazin-1-yl)phenyl)amino)piperidine-2,6-dione hydrochloride

  • CAS No. 2259851-45-9

  • Cat. No. CS-0652281
  • Purity≥97%
  • MDL No.None
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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

3-((4-(Piperazin-1-yl)phenyl)amino)piperidine-2,6-dione hydrochloride|CS-0652281

Structure of 2259851-45-9

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Description

This piperazine-containing heterocycle integrates a biologically active amine scaffold with enhanced solubility and stability under standard conditions. Designed for medicinal chemistry applications, the hydrochloride salt form improves handling and crystallinity while maintaining favorable pharmacokinetic properties in lead optimization workflows.

Application

This compound serves as a versatile scaffold for medicinal chemistry campaigns, enabling rapid access to complex heterocyclic architectures. The piperazinyl-phenyl-amino moiety provides enhanced solubility and hydrogen-bonding capacity, while the 2,6-dione core offers predictable reactivity in amide coupling and cyclization processes. Bench-stable and readily purified by standard methods, it functions as a key building block in the synthesis of bioactive molecules targeting CNS disorders and kinase pathways.

General Information

  • CAS No. 2259851-45-9
  • Cat. No. CS-0652281
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₁ClN₄O₂
  • Molecular Weight 324.81
  • Synonym(s) None
  • SMILES O=C1NC(C(CC1)NC2=CC=C(N3CCNCC3)C=C2)=O.Cl

Computational Chemistry Data

  • TPSA   73.47
  • LogP   0.7351
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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