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Structure of 225931-80-6
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Bis[(trimethylsilyl)methyl](1,5-cyclooctadiene)palladium(II) delivers a stable, moisture-tolerant Pd(II) source for cross-coupling reactions. The trimethylsilyl groups enhance solubility and reduce aggregation, while the 1,5-cyclooctadiene ligand facilitates controlled reductive elimination. This complex enables efficient C–C and C–heteroatom bond formation under mild conditions.
Bis[(trimethylsilyl)methyl](1,5-cyclooctadiene)palladium(II) serves as a stable, bench-ready palladium source for cross-coupling reactions, enabling efficient C–C bond formation via oxidative addition. Its trimethylsilylmethyl groups enhance functional group tolerance and facilitate in situ generation of reactive intermediates. The 1,5-cyclooctadiene ligand provides kinetic stability while allowing facile displacement during catalytic cycles, making it well-suited for Suzuki-Miyaura, Negishi, and Stille couplings in medicinal chemistry and process development workflows.
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅲ
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Hazard Statements : H228-H315-H319-H335
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Precautionary Statements : P210-P240-P241-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: