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CS-W001157 4
Total: USD 88.00

Ethyl 3-hydroxyphenylacetate

  • CAS No. 22446-38-4

  • Cat. No. CS-0030409
  • Purity≥97%
  • MDL No.MFCD07369387

*For research and further manufacturing use only, not for direct human use.

Ethyl 3-hydroxyphenylacetate|CS-0030409

Structure of 22446-38-4

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General Information

  • CAS No. 22446-38-4
  • Cat. No. CS-0030409
  • Purity ≥97%
  • MDL No. MFCD07369387
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O₃
  • Molecular Weight 180.20
  • Synonym(s) Ethyl 2-(3-hydroxyphenyl)acetate
  • SMILES O=C(OCC)CC1=CC=CC(O)=C1

Description

Ethyl 3-hydroxyphenylacetate features a phenolic hydroxyl group flanked by an ethyl ester and a benzylic alcohol, enabling selective derivatization. This trifunctional scaffold integrates readily into complex molecular architectures under mild conditions. The molecule exhibits enhanced solubility in polar organic solvents and stability under standard bench protocols, facilitating use in synthetic sequences requiring orthogonal reactivity.

Synthesis

  • Route1
    • null|null
      64-17-5
    • In-stock
      3-Hydroxyphenylacetic acid|CS-W001083
      621-37-4
    • ~99%
    • In-stock
      Ethyl 3-hydroxyphenylacetate|CS-0030409
      22446-38-4

    References

    • SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH; CHIOSIS, Gabriela; TALDONE, Tony; SUN, Weilin Patent: WO2011/44394 A1, 2011 ; Location in patent: Page/Page column 127-128 ;
  • Route2
    • null|null
      7664-93-9
    • In-stock
      3-Hydroxyphenylacetic acid|CS-W001083
      621-37-4
    • ~97%
    • In-stock
      Ethyl 3-hydroxyphenylacetate|CS-0030409
      22446-38-4

    References

    • Warner-Lambert Company; Cocensys, Incorporated Patent: US6124323 A1, 2000 ; US 6124323 A
  • Route3

    References

    • US5872138 A1, ; US 5872138 A

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.4978
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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