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CS-W001157 4
Total: USD 88.00

1,5-Dichloro-2,4-difluorobenzene

  • CAS No. 2253-30-7

  • Cat. No. CS-0060128
  • Molecule weight182.98
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1,5-Dichloro-2,4-difluorobenzene|CS-0060128

Structure of 2253-30-7

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General Information

  • CAS No. 2253-30-7
  • Cat. No. CS-0060128
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₂Cl₂F₂
  • Molecular Weight 182.98
  • Synonym(s) 1,3-Dichloro-4,6-difluorobenzene
  • SMILES C1=C(C(=CC(=C1Cl)F)F)Cl

Description

1,5-Dichloro-2,4-difluorobenzene features a symmetrically substituted aromatic core with two chlorine and two fluorine atoms positioned for orthogonal reactivity. This electron-deficient scaffold enables selective coupling under mild conditions, delivering high-yield access to functionalized intermediates in pharmaceutical and agrochemical synthesis. The molecule exhibits excellent bench stability and compatibility with diverse reaction environments.

Application

1,5-Dichloro-2,4-difluorobenzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of substituted aromatic scaffolds. Its orthogonal halogenation pattern facilitates sequential cross-coupling reactions under palladium catalysis, offering predictable regioselectivity. The compound exhibits excellent bench stability and compatibility with standard purification methods, making it well-suited for multi-step synthetic sequences requiring functional group tolerance and reliable reactivity.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.2716
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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