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Structure of 2246923-22-6
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2-Ethynylthiazole-4-carboxylic acid features a reactive alkyne group conjugated to an electron-deficient thiazole ring, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC). This scaffold integrates readily into bioconjugation workflows and modular synthesis, offering high functional group tolerance and stability under standard conditions.
2-Ethynylthiazole-4-carboxylic acid serves as a versatile building block for the synthesis of thiazole-based heterocycles and bioactive molecules. Its terminal alkyne functionality enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the carboxylic acid group supports direct amidation or esterification, facilitating conjugation in medicinal chemistry and materials science applications. The compound exhibits good bench stability and is readily purified by recrystallization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: