Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(5-((Tert-butoxycarbonyl)amino)-2-chlorophenyl)boronic acid

  • CAS No. 2246849-87-4

  • Cat. No. CS-0173676
  • Molecule weight271.51
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(5-((Tert-butoxycarbonyl)amino)-2-chlorophenyl)boronic acid|CS-0173676

Structure of 2246849-87-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 2246849-87-4
  • Cat. No. CS-0173676
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₅BClNO₄
  • Molecular Weight 271.51
  • Synonym(s) 5-BOC-Amino-2-chlorophenylboronic acid
  • SMILES O=C(NC1=CC=C(C(B(O)O)=C1)Cl)OC(C)(C)C

Description

This boronate reagent features a tert-butoxycarbonyl-protected amine and a chlorine substituent on the phenyl ring, enabling selective coupling in late-stage functionalization. The electron-deficient arylboronic acid unit delivers enhanced reactivity in Suzuki-Miyaura cross-coupling, while the Boc group ensures stability during storage and handling under standard conditions.

Application

(5-((Tert-butoxycarbonyl)amino)-2-chlorophenyl)boronic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. The boronic acid functionality enables palladium-catalyzed cross-coupling reactions, while the ortho-chloro group permits subsequent nucleophilic substitution or cyclization. The tert-butoxycarbonyl (Boc) protecting group offers excellent bench stability and compatibility with standard deprotection protocols, facilitating efficient multi-step synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   78.79
  • LogP   1.3668
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2246849-87-4 sigma2246849-87-4 manufacturer2246849-87-4 price2246849-87-4 structure2246849-87-4 SDSbuy 2246849-87-42246849-87-4 supplier2246849-87-4 uses2246849-87-4 molecular weightprice of 2246849-87-42246849-87-4 chemical name formula of 2246849-87-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label