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CS-W001157 4
Total: USD 88.00

2-Methyl-5-pyrimidinemethanol

  • CAS No. 2239-83-0

  • Cat. No. CS-W019609
  • Purity≥98%
  • MDL No.MFCD09414732
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Methyl-5-pyrimidinemethanol|CS-W019609

Structure of 2239-83-0

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Description

2-Methyl-5-pyrimidinemethanol features a pyrimidine core functionalized with a methyl group at C2 and a hydroxymethyl substituent at C5, delivering enhanced solubility and stability. This scaffold integrates readily into heterocyclic libraries, serving as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and nucleoside analogs.

Application

2-Methyl-5-pyrimidinemethanol serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrimidine-based scaffolds through standard functional group transformations. Its bench-stable nature and compatibility with common coupling reactions facilitate straightforward derivatization. The molecule functions effectively as a synthetic intermediate for heterocyclic compounds, particularly in the development of kinase inhibitors and nucleoside analogs.

General Information

  • CAS No. 2239-83-0
  • Cat. No. CS-W019609
  • Purity ≥98%
  • MDL No. MFCD09414732
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O
  • Molecular Weight None
  • Synonym(s) (2-Methylpyrimidin-5-yl)methanol; 5-Pyrimidinemethanol, 2-methyl- (7CI,8CI,9CI)
  • SMILES OCC1=CN=C(C)N=C1

Computational Chemistry Data

  • TPSA   46.01
  • LogP   0.27732
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P234-P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P312-P332+P313-P362+P364-P390-P403+P233-P405-P406-P501

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