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CS-W001157 4
Total: USD 88.00

3-(4-Bromophenyl)oxazolidin-2-one

  • CAS No. 223555-95-1

  • Cat. No. CS-0567900
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(4-Bromophenyl)oxazolidin-2-one|CS-0567900

Structure of 223555-95-1

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General Information

  • CAS No. 223555-95-1
  • Cat. No. CS-0567900
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈BrNO₂
  • Molecular Weight 242.07
  • Synonym(s) 3-(4-Bromophenyl)oxazolidine-2-one
  • SMILES O=C1OCCN1C2=CC=C(Br)C=C2

Description

3-(4-Bromophenyl)oxazolidin-2-one is a bench-stable, moisture-tolerant heterocyclic building block featuring a brominated aryl group. This electron-deficient oxazolidinone integrates readily into synthetic sequences requiring orthogonal functionalization. The para-bromophenyl moiety enables direct coupling via palladium-catalyzed cross-coupling reactions. Its rigid scaffold supports stereocontrolled transformations in complex molecule assembly.

Application

3-(4-Bromophenyl)oxazolidin-2-one serves as a versatile chiral building block in synthetic organic chemistry, enabling the construction of pharmaceutically relevant heterocycles and amino acid derivatives. Its stability under standard reaction conditions, combined with orthogonal functional group tolerance, facilitates downstream transformations including nucleophilic substitution and transition-metal-catalyzed couplings. The bromo substituent provides a direct handle for further diversification via cross-coupling reactions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   2.4057
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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