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(R)-3-Aminopyrrolidin-2-one hydrochloride

  • CAS No. 223407-19-0

  • Cat. No. CS-0094049
  • Purity≥95%
  • MDL No.MFCD14635509

*For research and further manufacturing use only, not for direct human use.

(R)-3-Aminopyrrolidin-2-one hydrochloride|CS-0094049

Structure of 223407-19-0

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General Information

  • CAS No. 223407-19-0
  • Cat. No. CS-0094049
  • Purity ≥95%
  • MDL No. MFCD14635509
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉ClN₂O
  • Molecular Weight 136.58
  • Synonym(s) (R)-3-Amino-pyrrolidin-2-one hydrochloride
  • SMILES O=C1NCC[C@H]1N.[H]Cl

Description

(R)-3-Aminopyrrolidin-2-one hydrochloride is a chiral building block featuring a stereochemically defined amine and lactam functionality. This bench-stable, moisture-tolerant compound integrates readily into medicinal chemistry campaigns, enabling direct access to complex nitrogen-containing scaffolds via straightforward derivatization.

Application

(R)-3-Aminopyrrolidin-2-one hydrochloride serves as a key chiral building block in medicinal chemistry, enabling efficient access to nitrogen-containing heterocycles. Its well-defined stereochemistry and amine functionality facilitate direct incorporation into peptidomimetics and bioactive scaffolds. The hydrochloride salt enhances stability and solubility, supporting straightforward handling and purification in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   -0.7446
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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