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Structure of 22328-78-5
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(S)-Ethyl piperidine-2-carboxylate is a chiral building block featuring a stereodefined piperidine core with a carboxylate ester at the 2-position. This configuration enables selective incorporation into bioactive molecules, particularly in medicinal chemistry campaigns targeting CNS modulators and kinase inhibitors. The ester group facilitates downstream transformations including hydrolysis, amidation, or reductive amination. Its bench-stable nature supports reliable handling under standard conditions.
(S)-Ethyl piperidine-2-carboxylate serves as a stereochemically defined chiral building block for the synthesis of bioactive molecules, particularly in medicinal chemistry. Its piperidine core provides a rigid, basic scaffold with favorable pharmacokinetic properties. The ester group enables straightforward derivatization via hydrolysis or nucleophilic substitution, while the (S)-configuration ensures predictable stereoselective outcomes in downstream transformations. Bench-stable and readily purified by standard chromatography, it functions effectively in multistep syntheses involving amide coupling, reductive amination, or heterocycle formation.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H225-H315-H319
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P280-P362-P370+P378-P501
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Lot numbers can be found on the outside label of a product: