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CS-W001157 4
Total: USD 88.00

2,2',3,3'-Tetrahydro-1,1'-spirobi[indene]-7,7'-diol

  • CAS No. 223137-87-9

  • Cat. No. CS-W018806
  • Purity≥96%
  • MDL No.MFCD16621090

*For research and further manufacturing use only, not for direct human use.

2,2',3,3'-Tetrahydro-1,1'-spirobi[indene]-7,7'-diol|CS-W018806

Structure of 223137-87-9

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General Information

  • CAS No. 223137-87-9
  • Cat. No. CS-W018806
  • Purity ≥96%
  • MDL No. MFCD16621090
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₁₆O₂
  • Molecular Weight 252.31
  • Synonym(s) 2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diol
  • SMILES OC1=CC=CC2=C1C3(CCC4=C3C(O)=CC=C4)CC2

Description

This spirobiindene diol features a rigid, chiral scaffold with two phenolic hydroxyl groups positioned for cooperative hydrogen bonding. The tetrahydroindene units provide enhanced stability and solubility in polar aprotic solvents, enabling use in asymmetric synthesis and supramolecular chemistry applications.

Application

2,2',3,3'-Tetrahydro-1,1'-spirobi[indene]-7,7'-diol serves as a rigid, chiral scaffold for asymmetric synthesis and molecular recognition studies. Its diol functionality enables selective derivatization and coordination in catalytic systems, while the spirocyclic framework imparts conformational stability and enhanced stereochemical control in ligand design and natural product synthesis.

Synthesis

  • Route1

    References

    • Tetrahedron Asymmetry, , vol. 10, # 1 p. 125 - 131
  • Route2
    • null|null
      458533-66-9
    • ~%
    • In-stock
      2,2',3,3'-Tetrahydro-1,1'-spirobi[indene]-7,7'-diol|CS-W018806
      223137-87-9

    References

    • Tetrahedron Asymmetry, , vol. 10, # 1 p. 125 - 131
  • Route3
    • null|null
      223137-67-5
    • ~%
    • In-stock
      2,2',3,3'-Tetrahydro-1,1'-spirobi[indene]-7,7'-diol|CS-W018806
      223137-87-9

    References

    • Tetrahedron Asymmetry, , vol. 10, # 1 p. 125 - 131

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   3.2763
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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