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CS-W001157 4
Total: USD 88.00

1-Bromo-3-iodopropane,98% (stabilized with Cu)

  • CAS No. 22306-36-1

  • Cat. No. CS-0199040
  • Purity98% (stabilized with Cu)
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Bromo-3-iodopropane,98% (stabilized with Cu)|CS-0199040

Structure of 22306-36-1

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General Information

  • CAS No. 22306-36-1
  • Cat. No. CS-0199040
  • Purity 98% (stabilized with Cu)
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₆BrI
  • Molecular Weight 248.89
  • Synonym(s) 3-Bromopropyl iodide
  • SMILES BrCCCI

Description

1-Bromo-3-iodopropane, stabilized with Cu, delivers a bifunctional alkylating agent with complementary reactivity. The bromine and iodine termini enable sequential coupling in cross-coupling cascades or stepwise functionalization. This bench-stable, moisture-tolerant reagent simplifies the construction of complex molecular architectures in synthetic organic chemistry workflows.

Application

1-Bromo-3-iodopropane, 98% (stabilized with Cu) serves as a versatile dihalogenated alkyl building block for C–C and C–heteroatom coupling reactions. The bromo and iodo termini enable sequential functionalization via palladium-catalyzed cross-coupling, while copper stabilization enhances shelf life and minimizes decomposition. Its linear aliphatic structure supports efficient synthesis of polyfunctional intermediates, including heterocyclic scaffolds and bioactive analogs, with predictable regioselectivity and compatibility in standard synthetic workflows.

Synthesis

  • Route1

    References

    • House,H.O. et al. Journal of Organic Chemistry, 1978 , vol. 43, p. 2153 - 2157

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07,GHS08,GHS09
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H225-H302-H315-H319-H341-H370-H373-H411
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P270-P273-P280-P302+P352-P330-P362+P364-P370+P378-P391-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.2064
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   2

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