Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Fluoropyridin-4-ol

  • CAS No. 22282-69-5

  • Cat. No. CS-W019270
  • Purity≥98%
  • MDL No.MFCD04114159
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Fluoropyridin-4-ol|CS-W019270

Structure of 22282-69-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

Description

2-Fluoropyridin-4-ol features a fluorine atom at the 2-position and a hydroxyl group at the 4-position on a pyridine ring, creating a polar, electron-deficient heterocycle. This arrangement enables direct functionalization at the 3- or 5-position, facilitating coupling reactions under mild conditions. The compound exhibits enhanced stability compared to analogous phenols and serves as a key building block in medicinal chemistry for kinase inhibitors and fluorescent probes.

Application

2-Fluoropyridin-4-ol serves as a versatile building block for constructing fluorinated heterocycles and bioactive molecules. Its reactivity enables direct nucleophilic substitution at the C2 position, facilitating the synthesis of substituted pyridines under mild conditions. The hydroxyl group offers orthogonal handling for derivatization, while the fluorine substituent enhances metabolic stability and modulates electronic properties. Bench-stable and compatible with standard synthetic workflows, it functions effectively in coupling reactions and scaffold elaboration for medicinal chemistry applications.

General Information

  • CAS No. 22282-69-5
  • Cat. No. CS-W019270
  • Purity ≥98%
  • MDL No. MFCD04114159
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄FNO
  • Molecular Weight 113.09
  • Synonym(s) 2-Fluoro-4-Hydroxypyridine
  • SMILES FC1=NC=CC(=C1)O

Computational Chemistry Data

  • TPSA   33.12
  • LogP   0.9263
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Fluoropyridin-4-ol sigma2-Fluoropyridin-4-ol manufacturer2-Fluoropyridin-4-ol price2-Fluoropyridin-4-ol structure2-Fluoropyridin-4-ol SDSbuy 2-Fluoropyridin-4-ol2-Fluoropyridin-4-ol supplier2-Fluoropyridin-4-ol uses2-Fluoropyridin-4-ol molecular weightprice of 2-Fluoropyridin-4-ol2-Fluoropyridin-4-ol chemical name formula of 2-Fluoropyridin-4-ol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label