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Structure of 2227488-62-0
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This chiral pyrrolidine derivative features a hydroxyl group at C4 and an amide linkage to a 2,6-dimethylphenyl moiety, offering enhanced solubility and stability under standard conditions. The stereochemistry at C2 and C4 enables precise molecular recognition in asymmetric synthesis and medicinal chemistry applications.
(2S,4R)-N-(2,6-Dimethylphenyl)-4-hydroxypyrrolidine-2-carboxamide serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptidomimetics. The hydroxypyrrolidine core provides a rigid, stereodefined scaffold with hydrogen-bonding capacity, while the N-aryl substitution enhances metabolic stability and modulates solubility. Its bench-stable nature and compatibility with standard coupling and functionalization reactions facilitate efficient route development for API candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P362+P364
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Lot numbers can be found on the outside label of a product: