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tert-Butyl cis-N-(4-amino-1-methyl-cyclohexyl)carbamate hydrochloride

  • CAS No. 2227199-12-2

  • Cat. No. CS-0185109
  • Molecule weight264.79
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl cis-N-(4-amino-1-methyl-cyclohexyl)carbamate hydrochloride|CS-0185109

Structure of 2227199-12-2

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General Information

  • CAS No. 2227199-12-2
  • Cat. No. CS-0185109
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₅ClN₂O₂
  • Molecular Weight 264.79
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N[C@@]1(C)CC[C@@H](N)CC1.[H]Cl

Description

tert-Butyl cis-N-(4-amino-1-methyl-cyclohexyl)carbamate hydrochloride features a sterically hindered cyclohexyl scaffold with a strategically positioned amino group and electron-rich amine functionality. This bench-stable derivative enables direct incorporation into peptide conjugation workflows, offering enhanced solubility in aqueous-organic mixtures while maintaining structural integrity under standard handling conditions.

Application

tert-Butyl cis-N-(4-amino-1-methyl-cyclohexyl)carbamate hydrochloride serves as a versatile building block for the synthesis of substituted cyclohexylamine derivatives. The protected amine and tertiary alcohol functionalities enable orthogonal transformations, while the hydrochloride salt enhances solubility and stability in aqueous and polar organic media. Its cis-configured ring system provides defined stereochemistry for applications in medicinal chemistry and heterocyclic scaffold construction.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   2.5929
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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