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CS-W001157 4
Total: USD 88.00

7-Hydroxy-3,4-dihydroquinolin-2(1H)-one Brexpiprazole Impurity

  • CAS No. 22246-18-0

  • Cat. No. CS-0167116
  • Purity≥97%
  • MDL No.MFCD06410891

*For research and further manufacturing use only, not for direct human use.

7-Hydroxy-3,4-dihydroquinolin-2(1H)-one  Brexpiprazole Impurity|CS-0167116

Structure of 22246-18-0

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General Information

  • CAS No. 22246-18-0
  • Cat. No. CS-0167116
  • Purity ≥97%
  • MDL No. MFCD06410891
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉NO₂
  • Molecular Weight 163.17
  • Synonym(s) None
  • SMILES O=C1NC2=C(CC1)C=CC(O)=C2

Synthesis

  • Route1
    • 3-Chloro-N-(3-methoxyphenyl)propanamide|CS-0073230
      21261-76-7
    • ~80%
    • 7-Hydroxy-3,4-dihydroquinolin-2(1H)-one  Brexpiprazole Impurity|CS-0167116
      22246-18-0

    References

    • UNICHEM LABORATORIES LIMITED Patent: WO2007/94009 A1, 2007 ; Location in patent: Page/Page column 6 ;
  • Route2
    • Aripiprazole impurity 23|CS-0313180
      50297-40-0
    • ~74%
    • 7-Hydroxy-3,4-dihydroquinolin-2(1H)-one  Brexpiprazole Impurity|CS-0167116
      22246-18-0

    References

    • WYETH Patent: WO2008/150848 A1, 2008 ; Location in patent: Page/Page column 132-133 ; WO 2008/150848 A1
  • Route3

    References

    • Naddaka, Vladimir; Davidi, Guy; Klopfer, Eyal; Arad, Oded; Kaspi, Joseph Patent: US2006/79690 A1, 2006 ; Location in patent: Page/Page column 6 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317-H412
Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   1.2769
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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