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CS-W001157 4
Total: USD 88.00

LANA-IN-1

  • CAS No. 2221-00-3

  • Cat. No. CS-W016178
  • Purity≥98%
  • MDL No.MFCD01074865

*For research and further manufacturing use only, not for direct human use.

LANA-IN-1|CS-W016178

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General Information

  • CAS No. 2221-00-3
  • Cat. No. CS-W016178
  • Purity ≥98%
  • MDL No. MFCD01074865
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉N₃
  • Molecular Weight 159.19
  • Synonym(s) 4-(1H-Imidazol-1-yl)aniline
  • SMILES NC(C=C1)=CC=C1N2C=CN=C2

Description

LANA-IN-1 is a potent, selective inhibitor of the latency-associated nuclear antigen (LANA) from Kaposi’s sarcoma-associated herpesvirus. This small molecule disrupts LANA-mediated tethering of viral episomes to host chromatin, effectively blocking latent persistence. Designed for use in antiviral research and mechanistic studies of herpesviral latency, it enables precise interrogation of viral genome maintenance without cytotoxic interference.

Application

LANA-IN-1 serves as a well-characterized, bench-stable inhibitor targeting the LANA protein of KSHV, enabling selective disruption of viral latency in experimental models. Its defined chemical structure facilitates consistent use in biochemical assays and supports downstream mechanistic studies involving viral persistence and reactivation pathways.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   43.84
  • LogP   1.4545
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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