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CS-W001157 4
Total: USD 88.00

1,4,5,6-Tetrahydrocyclopenta[c]pyrazole

  • CAS No. 2214-03-1

  • Cat. No. CS-W000731
  • Purity≥97%
  • MDL No.MFCD05663424

*For research and further manufacturing use only, not for direct human use.

1,4,5,6-Tetrahydrocyclopenta[c]pyrazole|CS-W000731

Structure of 2214-03-1

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General Information

  • CAS No. 2214-03-1
  • Cat. No. CS-W000731
  • Purity ≥97%
  • MDL No. MFCD05663424
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂
  • Molecular Weight 108.14
  • Synonym(s) 1H,4H,5H,6H-cyclopenta[c]pyrazole
  • SMILES C1(CCC2)=C2C=NN1

Description

1,4,5,6-Tetrahydrocyclopenta[c]pyrazole is a nitrogen-rich heterocyclic scaffold featuring a fused cyclopentane-pyrazole core. This rigid, electron-deficient framework enables integration into bioactive molecules and serves as a conformationally constrained mimic for pyrrole and indole systems in medicinal chemistry.

Application

1,4,5,6-Tetrahydrocyclopenta[c]pyrazole serves as a versatile heterocyclic scaffold in medicinal chemistry, enabling the construction of bioactive molecules through well-established functionalization at the 1- and 5-positions. Its stability under standard reaction conditions and compatibility with diverse coupling protocols facilitate efficient access to complex nitrogen-containing frameworks. The core structure functions as a key building block for targeted synthesis of pharmacologically relevant compounds.

Synthesis

  • Route1

    References

    • Justus Liebigs Annalen der Chemie, , vol. 536, p. 97,108
  • Route2

    References

    • Justus Liebigs Annalen der Chemie, , vol. 536, p. 97,108
  • Route3
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      120-92-3
    • ~%
    • In-stock
      1,4,5,6-Tetrahydrocyclopenta[c]pyrazole|CS-W000731
      2214-03-1

    References

    • Justus Liebigs Annalen der Chemie, , vol. 536, p. 97,108

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   0.8984
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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