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CS-W001157 4
Total: USD 88.00

2,5-Dibromopyridine-3,4-diamine

  • CAS No. 221241-11-8

  • Cat. No. CS-W004508
  • Purity≥97%
  • MDL No.MFCD15526814

*For research and further manufacturing use only, not for direct human use.

2,5-Dibromopyridine-3,4-diamine|CS-W004508

Structure of 221241-11-8

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General Information

  • CAS No. 221241-11-8
  • Cat. No. CS-W004508
  • Purity ≥97%
  • MDL No. MFCD15526814
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅Br₂N₃
  • Molecular Weight 266.92
  • Synonym(s) None
  • SMILES Brc1cnc(c(c1N)N)Br

Description

2,5-Dibromopyridine-3,4-diamine features two bromine substituents flanking a pyridine core with diamine functionality at the 3 and 4 positions. This electron-deficient heterocycle enables direct coupling in cross-coupling reactions, serving as a key scaffold for synthesizing functionalized pyridine derivatives under standard conditions.

Application

2,5-Dibromopyridine-3,4-diamine serves as a versatile building block for heterocyclic synthesis, enabling efficient construction of pyridine-based scaffolds through Pd-catalyzed cross-coupling reactions. The diamine functionality offers orthogonal reactivity for derivatization, while the bromine substituents provide reliable handles for further functionalization. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthetic campaigns in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.93
  • LogP   1.771
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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